3-O-ETHYL-L-ASCORBIC ACID by KimiKa, LLC (Formerly Cosphatech) (2024)

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  • 3-O-ETHYL-L-ASCORBIC ACID Datasheet
  • SDS

3-O-Ethyl-L-Ascorbic Acid, or Ethyl Ascorbic Acid is a molecule produced by modifying Ascorbic Acid, commonly known as Vitamin C. This modification is done to increase the molecule’s stability and enhance its transport through skin, as pure Vitamin C is easily degraded. In the body, the modifying group is removed and Vitamin C is restored in its natural form. Thus, Ethyl Ascorbic Acid retains the benefits of Vitamin C, such as antioxidant activity. Furthermore, it is even more potent in reducing skin darkening after UV exposure. It even has some additional effects, not observed in pure Ascorbic Acid, such as promoting nerve cell growth or reducing chemotherapy damage. Finally, the slower release also ensures that no toxic effects are observed when using this Vitamin C derivative.

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Name (CAS Number)
L-Ascorbic acid, 3-O-ethyl- (86404-04-8) Sign in to view

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Regulatory & Advisory Status

Name (CAS Number)

L-Ascorbic acid, 3-O-ethyl- (86404-04-8)

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Company

KimiKa, LLC (Formerly Cosphatech) is a leading supplier, manufacturer, and seller of raw materials for the personal care and cosmetics industries. They offer a wide range of high-quality products, including complexing agents, multifunctionals, emulsifiers, and antioxidants. The company's expertise combined with continuous expansion and innovation ensures great quality products and services for their customers.

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KimiKa, LLC (Formerly Cosphatech) makes their documentation available in the regions indicated below:

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3-O-ETHYL-L-ASCORBIC ACID by KimiKa, LLC (Formerly Cosphatech) (1) 3-O-ETHYL-L-ASCORBIC ACID by KimiKa, LLC (Formerly Cosphatech) (2) 3-O-ETHYL-L-ASCORBIC ACID by KimiKa, LLC (Formerly Cosphatech) (3) 3-O-ETHYL-L-ASCORBIC ACID by KimiKa, LLC (Formerly Cosphatech) (4) 3-O-ETHYL-L-ASCORBIC ACID by KimiKa, LLC (Formerly Cosphatech) (5)

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Chemical Class Categories
  • Alcohols
  • Heterocyclic Compounds
Functionality Categories
  • Skin Conditioning Agents ~ Miscellaneous

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KimiKa, LLC (Formerly Cosphatech)

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3-O-ETHYL-L-ASCORBIC ACID by KimiKa, LLC (Formerly Cosphatech) (2024)

FAQs

Is 3 0 ethyl ascorbic acid safe to use? ›

It is a semi-synthetic substance that is characterised by higher bioavailability, stability, solubility, and non-toxicity, as compared to its natural counterpart. This makes it a safe and stable product that can be used for a myriad of different applications, including in skincare products.

What is the difference between ethyl ascorbic acid and 3 O ethyl ascorbic acid? ›

Ethyl Ascorbic Acid is also known as 3-O-Ethyl-L-ascorbic Acid. It is a molecule formed by modifying Ascorbic Acid or, as we know it better, vitamin C. So why is the modification done? Well, to make the compound more stable, of course.

What is 3-O-ethyl-L-ascorbic acid? ›

3-O-ethyl-l-ascorbic acid (EA) is an l-ascorbic acid derivative with an ethyl group at the third carbon position. This structural modification protects the 3-OH group from ionization, and thus the molecule from oxidation, but also results in changes in the physicochemical properties.

Is ethyl ascorbic acid a good vitamin C? ›

Overall, Ethyl Ascorbic Acid is a very promising but not a fully proven Vitamin C derivative. It's worth a try, especially if you are after Vitamin C's skin-brightening effects.

What not to mix with ethyl ascorbic acid? ›

Vitamin C is effectively an acid (it's sometimes known as ascorbic acid), so layering it with AHAs and BHAs like glycolic, salicylic, and lactic acids is a big no-no.

What are the disadvantages of ethyl ascorbic acid? ›

The anti-inflammatory properties of Vitamin C help to soothe the irritated skin. Hence, it has become the key ingredient in many skincare products. The only drawback of this magical beauty ingredient is that it is highly unstable and easily oxidizes when exposed to light and air, thereby reducing its efficiency.

Is 3-O ethyl ascorbic acid anti-aging? ›

3-O ethyl ascorbic acid is a stable, water- and oil-soluble derivative of pure vitamin C (ascorbic acid) that offers all of the primary benefits vitamin C is known for, such as brightening, wrinkle reduction, visible firming, fading hyperpigmentation to restore a more even skin tone and offsetting numerous triggers of ...

Which is more effective, ethyl ascorbic acid or L-ascorbic acid? ›

The bottom line is that your typical L-ascorbic acid product could irritate your skin and oxidize in a week. So, when choosing your vitamin C serum, do so carefully and put chemical composition over brands and skincare hype. When in doubt, always choose a vitamin C product made with 3-O-Ethyl-Ascorbic acid!

Can you use ethyl ascorbic acid in the morning? ›

Apply a few drops to the face in the morning and evening. Avoid the eye contour and contact with eyes. Use sun protection during the day.

Can I use ethyl ascorbic acid with retinol? ›

Engelman and Dr. Mraz Robinson say yes, retinol and vitamin C should both absolutely be a part of your skincare routine. Having retinol and vitamin C in your skincare regimen is a great idea since both are powerful anti-agers that address skin appearance as well as skin health.

Which form of vitamin C is best for skin? ›

It is important to remember that while derivatives of vitamin C can be absorbed into the skin, they will not always convert into active vitamin C, therefore products that include L-ascorbic acid (pure vitamin C for skin) are preferable.

Can 3-O-ethyl ascorbic acid be used with niacinamide? ›

Here's the good news: Yes, you can use products that contain vitamin C with products that contain niacinamide in your skin care routine.

What is the best percentage of ethyl ascorbic acid? ›

Usage levels of 3-O ethyl ascorbic acid in skin care typically fall between 0.5–5%. Due to its stability, lesser amounts are needed compared with pure vitamin C. Levels above 5% may also be used, depending on desired benefits. Amounts up to 30% have been shown to be non-irritating on human skin samples.

What does the L mean in L-ascorbic acid? ›

Ascorbic acid exists as two enantiomers (mirror-image isomers), commonly denoted " l" (for "levo") and " d" (for "dextro"). The l isomer is the one most often encountered: it occurs naturally in many foods, and is one form ("vitamer") of vitamin C, an essential nutrient for humans and many animals.

Which is better vitamin C or ascorbic acid? ›

While they are not necessarily wrong, most vendors and professionals exclusively view ascorbic acid as the synthetic alternative to natural vitamin C. This is not to say natural vitamin C has no value, but ascorbic acid is more useful when you have a serious deficiency that requires immediate attention.

Is ascorbic acid a safety concern? ›

Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

When should you not use ascorbic acid? ›

If you are pregnant, talk to your doctor before taking more than 1,000 mg of vitamin C. People with sickle cell anemia, as well as people with a metabolic disorder called G6PD, can potentially have serious side-effects from taking high levels of vitamin C.

What percentage of ascorbic acid is best? ›

Concentration: The sweet spot for the concentration level is between 10 and 20 percent. You definitely want a concentration that's higher than 8 percent for maximum effectiveness. But going over 20 percent could lead to irritation and doesn't increase its benefit.

How much ascorbic acid is safe? ›

The upper limit for all adults is 2,000 mg a day. Although too much dietary vitamin C is unlikely to be harmful, large doses of vitamin C supplements might cause: Diarrhea. Nausea.

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